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Science 5 February 1982:
Vol. 215. no. 4533, pp. 683 - 685
DOI: 10.1126/science.7058333
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Articles

Science, Vol 215, Issue 4533, 683-685
Copyright © 1982 by American Association for the Advancement of Science

articles

Histone proteins in HeLa S3 cells are synthesized in a cell cycle stage specific manner

F Marashi, L Baumbach, R Rickles, F Sierra, JL Stein, and GS Stein

The synthesis of histone proteins in G1 and S phase HeLa S3 cells was examined by two-dimensional electrophoretic fractionation of nuclear and total cellular proteins. Newly synthesized histones were detected only in S phase cells. Histone messenger RNA sequences, as detected by hybridization with cloned human histone genes, were present in the cytoplasm of S phase but not G1 cells.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Clustering of human H1 and core histone genes.
N Carozzi, F Marashi, M Plumb, S Zimmerman, A Zimmerman, L. Coles, Wells JR, G Stein, and J Stein (1984)
Science 224, 1115-1117
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