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Science 5 February 1982: Vol. 215. no. 4533, pp. 679 - 682 DOI: 10.1126/science.7058332
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Articles
Science, Vol 215, Issue 4533, 679-682
Copyright © 1982 by American Association for the Advancement of Science
DNA sequence of a gene encoding a BALB/c mouse Ld transplantation antigen
KW Moore,
BT Sher,
YH Sun,
KA Eakle,
and
L Hood
The sequence of a gene, denoted 27.5, encoding a transplantation antigen for the BALB/c mouse has been determined. Gene transfer studies and comparison of the translated sequence with the partial amino acid sequence of the Ld transplantation antigen establish that gene 27.5 encodes an Ld polypeptide. A comparison of the gene 27.5 sequence with several complementary DNA sequences suggests that the BALB/c mouse may contain a number of closely related L-like genes. Gene 27.5 has eight exons that correlate with the structural domains of the transplantation antigen.
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