Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 15 January 1982:
Vol. 215. no. 4530, pp. 293 - 294
DOI: 10.1126/science.7053576
Prev | Table of Contents | Next

Articles

Science, Vol 215, Issue 4530, 293-294
Copyright © 1982 by American Association for the Advancement of Science

articles

Prenatal exposure to the herbicide 2,4-dichlorophenyl-p-nitrophenyl ether destroys the rodent Harderian gland

LE Gray Jr, RJ Kavlock, N Chernoff, J Ferrell, J McLamb, and J Ostby

Exposure of mice to the herbicide 2,4-dichlorophenyl-p-nitrophenyl ether during gestation produces abnormalities that are not readily apparent at birth but become obvious as the pups mature. By 2 weeks after birth there are severe intraorbital defects resulting from destruction of the Harderian glands behind the eyes. This effect is noticeable only postnatally because the Harderian gland does not grow or function until after birth.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Lung hypoplasia in the nitrofen model of congenital diaphragmatic hernia occurs early in development.
T. W. Guilbert, S. A. Gebb, and J. M. Shannon (2000)
Am J Physiol Lung Cell Mol Physiol 279, L1159-L1171
   Abstract »    Full Text »    PDF »
Effects of Pesticides and Toxic Substances On Behavioral and Morphological Reproductive Development: Endocrine Versus Nonendocrine Mechanisms.
L. E. Gray JR and J. Ostby (1998)
Toxicology and Industrial Health 14, 159-184
   Abstract »    PDF »
Toxicant-disease-environment interactions associated with suppression of immune system, growth, and reproduction.
W. Porter, R Hinsdill, A Fairbrother, L. Olson, J Jaeger, T Yuill, S Bisgaard, W. Hunter, and K Nolan (1984)
Science 224, 1014-1017
   Abstract »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)