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Science 1 January 1982:
Vol. 215. no. 4528, pp. 81 - 82
DOI: 10.1126/science.7053563
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Articles

Science, Vol 215, Issue 4528, 81-82
Copyright © 1982 by American Association for the Advancement of Science

articles

beta, gamma-Peroxy analogs of adenosine and guanosine triphosphate: synthesis and biological activity

MS Rosendahl and NJ Leonard

Extended analogs of adenosine triphosphate (ATP) and guanosine triphosphate (GTP), in which a peroxide bridge replaces the terminal bridge-oxygen of the triphosphate chain, have been synthesized. The ability of beta, gamma-peroxy-ATP to inhibit or substitute for ATP in representative enzyme systems and that of beta, gamma-peroxy-GTP, for FTP in protein synthesis was tested.




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Science. ISSN 0036-8075 (print), 1095-9203 (online)