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Science 11 December 1981:
Vol. 214. no. 4526, pp. 1251 - 1253
DOI: 10.1126/science.7029715
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Articles

Science, Vol 214, Issue 4526, 1251-1253
Copyright © 1981 by American Association for the Advancement of Science

articles

Autoimmune encephalomyelitis: simultaneous identification of T and B cells in the target organ

U Traugott, E Shevach, J Chiba, HJ Stone, and CS Raine

Monoclonal antibodies to guinea pig T cells and antibodies to guinea pig immunoglobulin G were used in immunofluorescence studies to identify T and B cells in central nervous system tissue from guinea pigs with acute autoimmune encephalomyelitis. T cells appeared before B cells and were distributed within the white matter parenchyma, while B cells remained in perivascular spaces.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Multiple sclerosis: distribution of T cell subsets within active chronic lesions.
U Traugott, E. Reinherz, and C. Raine (1983)
Science 219, 308-310
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