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Science 27 November 1981:
Vol. 214. no. 4524, pp. 1038 - 1039
DOI: 10.1126/science.7302575

Articles

Science, Vol 214, Issue 4524, 1038-1039
Copyright © 1981 by American Association for the Advancement of Science


articles

Stimulation of intestinal calcium transport and bone calcium mobilization by prolactin in vitamin D-deficient rats

DN Pahuja and HF DeLuca

In vitamin D-deficient rats intestinal calcium transport increased significantly 4 hours after an injection of prolactin, reached a maximum after 8 hours, and declined to preinjection levels after 24 hours. Similarly, in vitamin D-deficient rats fed a diet low in calcium or phosphorus prolactin stimulated an increase in serum calcium in both groups and an increase in serum phosphorus in the rats fed the diet low in phosphorus. Thus it appears that prolactin affects organs involved in calcium regulation in a manner that is independent of the vitamin D endocrine system.


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