Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 20 November 1981:
Vol. 214. no. 4523, pp. 926 - 928
DOI: 10.1126/science.7302568
Prev | Table of Contents | Next

Articles

Science, Vol 214, Issue 4523, 926-928
Copyright © 1981 by American Association for the Advancement of Science

articles

Regenerating axons reclaim sensory targets from collateral nerve sprouts

PC Jackson and J Diamond

There is a critical period for the sprouting of intact low-threshold mechanosensory cutaneous nerves in rats; functional invasion of adjacent denervated skin does not occur in animals older than about 20 days of age, and it is largely confined to denervated skin within the "domain" of the parent dermatome. These nerves can regenerate readily in the adult, however, and such regenerating nerves do not respect domain borders; moreover, they functionally displace endings of intact nerves that earlier had sprouted into denervated skin.




To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)