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Science 6 November 1981:
Vol. 214. no. 4521, pp. 659 - 660
DOI: 10.1126/science.6945674
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Articles
Science, Vol 214, Issue 4521, 659-660
Copyright © 1981 by American Association for the Advancement of Science
X-linked ichthyosis: increased blood cholesterol sulfate and electrophoretic mobility of low-density lipoprotein
EH Epstein Jr,
RM Krauss,
and
CH Shackleton
Plasma cholesterol sulfate concentration is increased in patients with recessive X-linked ichthyosis, a disease in which steroid sulfatase activity is absent. In these patients, cholesterol sulfate is found primarily in the low-density lipoprotein fraction of plasma, and the electrophoretic mobility of these lipoproteins is greatly increased.
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