Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Site Tools

  • AAAS
  • Subscribe
  • Feedback

Site Search

Search Advanced

Science 23 October 1981:
Vol. 214. no. 4519, pp. 466 - 468
DOI: 10.1126/science.7291988
Prev | Table of Contents | Next

Articles

Science, Vol 214, Issue 4519, 466-468
Copyright © 1981 by American Association for the Advancement of Science

articles

Choline stimulates nicotinic receptors on adrenal medullary chromaffin cells to induce catecholamine secretion

RW Holz and RA Senter

Choline stimulated secretion of catecholamines from primary dissociated cultures of bovine adrenal medullary chromaffin cells by interacting with nicotinic receptors. Secretion was readily detected at a choline concentration of 1 millimole per liter and was maximal at 3 to 10 millimoles per liter; it was completely calcium-dependent. Further analysis suggested that choline acts as a partial nicotinic agonist.




To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)