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Science 18 September 1981:
Vol. 213. no. 4514, pp. 1383 - 1385
DOI: 10.1126/science.6455737
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Articles

Science, Vol 213, Issue 4514, 1383-1385
Copyright © 1981 by American Association for the Advancement of Science

articles

Phosphorylation of smooth muscle myosin: evidence for cooperativity between the myosin heads

A Persechini and DJ Hartshorne

The relationship between the actin-activated adenosinetriphosphatase activity of smooth muscle myosin and the extent of myosin light chain phosphorylation is nonlinear. It is suggested that the phosphorylation of the two heads of smooth muscle myosin is an ordered process and that the two heads are influenced by cooperative interactions.


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