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Science 11 September 1981:
Vol. 213. no. 4513, pp. 1263 - 1264
DOI: 10.1126/science.7022653
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Articles

Science, Vol 213, Issue 4513, 1263-1264
Copyright © 1981 by American Association for the Advancement of Science

articles

Immunohistochemical demonstration of a testicular substance related to luteinizing hormone-releasing hormone

WK Paull, CM Turkelson, CR Thomas, and A Arimura

A substance related to luteinizing hormone-releasing hormone was demonstrated, by immunohistochemical procedures, in the cytoplasm of interstitial cells within the rat testes. In many seminiferous tubules, nuclei of spermatogonial cells were also immunopositive. Both cytoplasmic and nuclear fractions of testicular homogenates contain immunoreactive compounds, and this report identifies which cell types contain this substance. The localization of a peptide hormone within the nucleus of a target cell population may indicate its mode of action.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Immunization of pigs against chicken gonadotropin-releasing hormone-II and lamprey gonadotropin-releasing hormone-III: Effects on gonadotropin secretion and testicular function.
A. Bowen, S. Khan, L. Berghman, J. D. Kirby, R .P. Wettemann, and J. A. Vizcarra (2006)
J Anim Sci 84, 2990-2999
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Gonadal Peptides as Mediators of Development and Functional Control of the Testis: An Integrated System with Hormones and Local Environment.
L. Gnessi, A. Fabbri, and G. Spera (1997)
Endocr. Rev. 18, 541-609
   Abstract »    Full Text »    PDF »
Yeast mating pheromone activates mammalian gonadotrophs: evolutionary conservation of a reproductive hormone?.
E Loumaye, J Thorner, and K. Catt (1982)
Science 218, 1323-1325
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