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Science 21 August 1981:
Vol. 213. no. 4510, pp. 909 - 910
DOI: 10.1126/science.7256284
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Articles

Science, Vol 213, Issue 4510, 909-910
Copyright © 1981 by American Association for the Advancement of Science

articles

Natural toxicants in human foods: psoralens in raw and cooked parsnip root

GW Ivie, DL Holt, and MC Ivey

Parsnip root contains three photoactive, mutagenic, and photocarcinogenic psoralens in a total concentration of about 40 parts per million. These chemicals are not destroyed by normal cooking procedures (boiling or microwave); thus humans are exposed to appreciable levels of psoralens through the consumption of parsnip and possibly other psoralen-containing foodstuffs. The toxicologic consequences to man of such exposure may be speculated on the basis of medicinal and laboratory studies, but epidemiologic data are not available.


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Enhancement of PUVA Phototoxic Effects Following Celery Ingestion: Cool Broth Also Can Burn.
L. Puig and J. M. d. Moragas (1994)
Arch Dermatol 130, 809-810
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The Use of Medicinal Herbs by Human Immunodeficiency Virus-Infected Patients.
W. J. Kassler, P. Blanc, and R. Greenblatt (1991)
Arch Intern Med 151, 2281-2288
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Severe Phototoxic Burn Following Celery Ingestion.
B. Ljunggren (1990)
Arch Dermatol 126, 1334-1336
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Phytophotodermatitis From Celery Among Grocery Store Workers.
P. J. Seligman, C. G. T. Mathias, M. A. O'Malley, R. C. Beier, L. J. Fehrs, W. S. Serrill, and W. E. Halperin (1987)
Arch Dermatol 123, 1478-1482
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Dietary carcinogens and anticarcinogens. Oxygen radicals and degenerative diseases.
B. Ames (1983)
Science 221, 1256-1264
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Metabolic Detoxification: Mechanism of Insect Resistance to Plant Psoralens.
G. W. IVIE, D. L. BULL, R. C. BEIER, N. W. PRYOR, and E. H. OERTLI (1983)
Science 221, 374-376
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Psoralen phototoxicity: correlation with serum and epidermal 8-methoxypsoralen and 5-methoxypsoralen in the guinea pig.
A Kornhauser, W. Wamer, and A. Giles Jr (1982)
Science 217, 733-735
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