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Science 12 June 1981:
Vol. 212. no. 4500, pp. 1288 - 1289
DOI: 10.1126/science.7195073
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Articles

Science, Vol 212, Issue 4500, 1288-1289
Copyright © 1981 by American Association for the Advancement of Science

articles

Reward-induced stereotypy: modulation by the hippocampus

LD Devenport, JA Devenport, and FA Holloway

In animals with hippocampal damage, the signaled administration of reward is sufficient to induce the sort of behavioral sterotypy and locomotion that heretofore has been observed only after drug administration. Haloperidol returns these behaviors to normal. The interaction of the hippocampus with reward helps to explain many well-known characteristics of animals with lesions in the hippocampus and may have relevance for catecholamine-based clinical disorders.


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