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Science 1 May 1981:
Vol. 212. no. 4494, pp. 559 - 560
DOI: 10.1126/science.7209553
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Articles

Science, Vol 212, Issue 4494, 559-560
Copyright © 1981 by American Association for the Advancement of Science

articles

Tyrosine increases blood pressure in hypotensive rats

LA Conlay, TJ Maher, and RJ Wurtman

Administration of tyrosine, the amino acid precursor of catecholamines, increased blood pressure 38 to 49 percent in rats made acutely hypotensive by hemorrhage; other large neutral amino acids were ineffective. Tyrosine's effect was abolished by adrenalectomy, suggesting that, in hypotensive animals, it acts by accelerating the peripheral synthesis and release of catecholamines.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Supplemental Dietary Tyrosine in Sepsis and Acute Hemorrhagic Shock.
R. Simon, W. Wetzel, K. Winsey, S. M. Levenson, and A. A. Demetriou (1987)
Arch Surg 122, 78-81
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