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Science 24 April 1981:
Vol. 212. no. 4493, pp. 446 - 452
DOI: 10.1126/science.6451928
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Articles

Science, Vol 212, Issue 4493, 446-452
Copyright © 1981 by American Association for the Advancement of Science

articles

Cross-contamination of cells in culture

WA Nelson-Rees, DW Daniels, and RR Flandermeyer

Lists are presented of references to all known publications describing cell properties that serve to characterize (i) known strains of HeLa and purported human cell lines indicated as HeLa contaminants, (ii) strains of human cell lines contaminated with human but non-HeLa cells, and (iii) strains of cells contaminated by cells from one or more other species. Frequencies of cell cross-contaminations are cited and references are presented to relatively simple techniques that could serve to detect such contamination.


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