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Science 27 March 1981:
Vol. 211. no. 4489, pp. 1444 - 1445
DOI: 10.1126/science.7466403
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Articles

Science, Vol 211, Issue 4489, 1444-1445
Copyright © 1981 by American Association for the Advancement of Science

articles

Potent contact allergen in the rubber plant guayule (Parthenium argentatum)

E Rodriguez, GW Reynolds, and JA Thompson

Chemical and dermatotoxicological investigations of the natural and processed resin of the Mexican rubber plant, guayule (Parthenium argentatum), has established the presence of a sesquiterpene cinnamic acid ester (guayulin A) that is a potent elicitor of allergic contact dermatitis in experimental animals. The guayule contact allergen is comparable to the poison ivy skin allergens as an elicitor of dermatitis in sensitized guinea pigs.




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Science. ISSN 0036-8075 (print), 1095-9203 (online)