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Science 27 March 1981: Vol. 211. no. 4489, pp. 1431 - 1433 DOI: 10.1126/science.7466400
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Articles
Science, Vol 211, Issue 4489, 1431-1433
Copyright © 1981 by American Association for the Advancement of Science
Repair of the ultraviolet-irradiated male genome in fertilized mouse eggs
B Brandriff
and
RA Pedersen
Unscheduled DNA synthesis occurred in both male and female pronuclei of the mouse zygote in response to irradiation with ultraviolet light, indicating a capacity for excision repair. Furthermore, damage to DNA of the male gamete before fertilization can be repaired after the sperm enters the egg cytoplasm.
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