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Science 13 March 1981:
Vol. 211. no. 4487, pp. 1179 - 1180
DOI: 10.1126/science.6258228
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Articles

Science, Vol 211, Issue 4487, 1179-1180
Copyright © 1981 by American Association for the Advancement of Science

articles

Growth factors modulate gonadotropin receptor induction in granulosa cell cultures

JS Mondschein and DW Schomberg

Epidermal growth factor and fibroblast growth factor inhibited follicle-stimulating hormone-dependent induction of luteinizing hormone receptor in cultured ovarian granulosa cells of the rat. In contrast, platelet-derived growth factor potentiated the induction of luteinizing hormone receptor by follicle-stimulating hormone. These results indicate that growth factors, well known for their effects on mitosis and DNA synthesis in cultured mammalian cells, are also able to modulate hormone-dependent differentiation in an endocrine target cell.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Microarray analysis of insulin-like growth factor-I-induced changes in messenger ribonucleic acid expression in cultured porcine granulosa cells: Possible role of insulin-like growth factor-I in angiogenesis.
J. A. Grado-Ahuir, P. Y. Aad, G. Ranzenigo, F. Caloni, F. Cremonesi, and L. J. Spicer (2009)
J Anim Sci 87, 1921-1933
   Abstract »    Full Text »    PDF »
Epidermal Growth Factor (EGF) Receptor Ligands in the Chicken Ovary: I. Evidence for Heparin-Binding EGF-Like Growth Factor (HB-EGF) as a Potential Oocyte-Derived Signal to Control Granulosa Cell Proliferation and HB-EGF and Kit Ligand Expression.
Y. Wang, J. Li, C. Ying Wang, A. H. Yan Kwok, and F. C. Leung (2007)
Endocrinology 148, 3426-3440
   Abstract »    Full Text »    PDF »
Luteinizing Hormone-Dependent Activation of the Epidermal Growth Factor Network Is Essential for Ovulation.
M. Hsieh, D. Lee, S. Panigone, K. Horner, R. Chen, A. Theologis, D. C. Lee, D. W. Threadgill, and M. Conti (2007)
Mol. Cell. Biol. 27, 1914-1924
   Abstract »    Full Text »    PDF »
Role of the Epidermal Growth Factor Network in Ovarian Follicles.
M. Conti, M. Hsieh, J.-Y. Park, and Y.-Q. Su (2006)
Mol. Endocrinol. 20, 715-723
   Abstract »    Full Text »    PDF »
Epidermal Growth Factor-Mediated Inhibition of Follicle-Stimulating Hormone-Stimulated StAR Gene Expression in Porcine Granulosa Cells Is Associated with Reduced Histone H3 Acetylation.
R. Rusovici, Y. Y. Hui, and H. A. LaVoie (2005)
Biol Reprod 72, 862-871
   Abstract »    Full Text »    PDF »
Basic fibroblast growth factor expression in isolated small human ovarian follicles.
J.H. Quennell, J-A.L. Stanton, and P.R. Hurst (2004)
Mol. Hum. Reprod. 10, 623-628
   Abstract »    Full Text »    PDF »
Cloning of Epidermal Growth Factor (EGF) and EGF Receptor from the Zebrafish Ovary: Evidence for EGF as a Potential Paracrine Factor from the Oocyte to Regulate Activin/Follistatin System in the Follicle Cells.
Y. Wang and W. Ge (2004)
Biol Reprod 71, 749-760
   Abstract »    Full Text »    PDF »
In Vivo Effect of Epidermal Growth Factor, Interleukin-1{beta}, and Interleukin-1RA on Equine Preovulatory Follicles.
A. Martoriati, G. Duchamp, and N. Gerard (2003)
Biol Reprod 68, 1748-1754
   Abstract »    Full Text »    PDF »
Spatiotemporal Expression of Epidermal Growth Factor Receptor Messenger RNA and Protein in the Hamster Ovary: Follicle Stage-Specific Differential Modulation by Follicle-Stimulating Hormone, Luteinizing Hormone, Estradiol, and Progesterone.
K. Garnett, J. Wang, and S. K. Roy (2002)
Biol Reprod 67, 1593-1604
   Abstract »    Full Text »    PDF »
Interactions Between Follicle-Stimulating Hormone and Growth Factors in Modulating Secretion of Steroids and Inhibin-Related Peptides by Nonluteinized Bovine Granulosa Cells.
C. Glister, D. S. Tannetta, N. P. Groome, and P. G. Knight (2001)
Biol Reprod 65, 1020-1028
   Abstract »    Full Text »    PDF »
Apoptosis of Granulosa Cells and Female Infertility in Achondroplastic Mice Expressing Mutant Fibroblast Growth Factor Receptor 3G374R.
A. Amsterdam, K. Kannan, D. Givol, Y. Yoshida, K. Tajima, and A. Dantes (2001)
Mol. Endocrinol. 15, 1610-1623
   Abstract »    Full Text »    PDF »
Ovarian Surface Epithelium: Biology, Endocrinology, and Pathology.
N. Auersperg, A. S. T. Wong, K.-C. Choi, S. K. Kang, and P. C. K. Leung (2001)
Endocr. Rev. 22, 255-288
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The mechanism of action of epidermal growth factor and transforming growth factor {alpha} on aromatase activity in granulosa cells from polycystic ovaries.
A. Misajon, P. Hutchinson, N. Lolatgis, A. O. Trounson, and G. Almahbobi (1999)
Mol. Hum. Reprod. 5, 96-103
   Abstract »    Full Text »    PDF »
Insulin Resistance Associated with Androgen Excess in Women with Autoantibodies to the Insulin Receptor.
S. I. TAYLOR, R. F. DONS, E. HERNANDEZ, J. ROTH, and P. GORDEN (1982)
Ann Intern Med 97, 851-855
   Abstract »    PDF »


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