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Science 6 March 1981:
Vol. 211. no. 4486, pp. 1052 - 1054
DOI: 10.1126/science.7008197
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Articles

Science, Vol 211, Issue 4486, 1052-1054
Copyright © 1981 by American Association for the Advancement of Science

articles

Living tissue formed in vitro and accepted as skin-equivalent tissue of full thickness

E Bell, HP Ehrlich, DJ Buttle, and T Nakatsuji

Living skin-equivalent grafts consisting of fibroblasts cast in collagen lattices and seeded with epidermal cells were successfully grafted onto the donors of the cells. The grafts were vascularized, did not evoke a homograft reaction, inhibited wound contraction, filled the wound space, and persisted.


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