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Science 6 March 1981:
Vol. 211. no. 4486, pp. 1002 - 1013
DOI: 10.1126/science.7008196
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Articles

Science, Vol 211, Issue 4486, 1002-1013
Copyright © 1981 by American Association for the Advancement of Science

articles

Clocked cell cycle clocks

LN Edmunds Jr and KJ Adams

The cell division cycle of both mammalian cells and microorganisms, which apparently has both deterministic and probabilistic features, is a clock of sorts in that the sequence of events that comprise it measures time under a given set of environmental conditions. The cell division cycle may itself be regulated by a programmable clock that, under certain conditions, can generate circadian periodicities by interaction with a circadian pacemaker. These clocks must insert time segments into the cell division cycle in order to generate the observed variability in cellular generation times.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Growth of Prochlorococcus, a Photosynthetic Prokaryote, in the Equatorial Pacific Ocean.
D. Vaulot, D. Marie, R. J. Olson, and S. W. Chisholm (1995)
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Biochemical modeling of an autonomously oscillatory circadian clock in Euglena.
K Goto, D. Laval-Martin, and L. Edmunds Jr (1985)
Science 228, 1284-1288
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Science. ISSN 0036-8075 (print), 1095-9203 (online)