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Science 13 February 1981:
Vol. 211. no. 4483, pp. 667 - 674
DOI: 10.1126/science.6256857
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Articles

Science, Vol 211, Issue 4483, 667-674
Copyright © 1981 by American Association for the Advancement of Science

articles

Gene expression in eukaryotes

DD Brown

Gene expression in eukaryotes is influenced by a wide variety of mechanisms including the loss, amplification, and rearrangement of genes. Genes are differentially transcribed, and the RNA transcripts are variably utilized. Multigene families regulate the amount, the diversity, and the timing of gene expression. The present level of understanding of gene expression in eukaryotes is attributable mainly to biochemical methods rather than to traditional genetics. The new techniques that permit analysis and modification of purified genes of known function will identify both the control regions in eukaryotic genes as well as the molecules within cell that influence gene expression.


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