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Science 6 February 1981:
Vol. 211. no. 4482, pp. 601 - 603
DOI: 10.1126/science.7455701

Articles

Science, Vol 211, Issue 4482, 601-603
Copyright © 1981 by American Association for the Advancement of Science


articles

Effects of vasopressin on human memory functions

H Weingartner, P Gold, JC Ballenger, SA Smallberg, R Summers, DR Rubinow, RM Post, and FK Goodwin

Arginine vasopressin and a number of its synthetic analogs augment memory functions in experimental animals.One of these analogs, 1-desamino-8-D-arginine vasopressin (DDAVP), influences human learning and memory. Cognitively unimpaired, as well as cognitively impaired adults, treated with DDAVP for a period of several days, learn information more effectively, as measured by the completeness, organization, and consistency (reliability) of recall. DDAVP also appears to reverse partially the retrograde amnesia that follows electroconvulsive treatment.


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