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Science 12 December 1980:
Vol. 210. no. 4475, pp. 1267 - 1269
DOI: 10.1126/science.7434030

Articles

Science, Vol 210, Issue 4475, 1267-1269
Copyright © 1980 by American Association for the Advancement of Science


articles

Light suppresses melatonin secretion in humans

AJ Lewy, TA Wehr, FK Goodwin, DA Newsome, and SP Markey

Bright artificial light suppressed nocturnal secretion of melatonin in six normal human subjects. Room light of less intensity, which is sufficient to suppress melatonin secretion in other mammals, failed to do so in humans. In contrast to the results of previous experiments in which ordinary room light was used, these findings establish that the human response to light is qualitatively similar to that of other mammals.


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Sensitivity of the Human Circadian Pacemaker to Moderately Bright Light.
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Influence of Melatonin Treatment on Human Circadian Rhythmicity before and after a Simulated 9-Hr Time Shift.
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J Biol Rhythms 6, 235-248
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Altered Waveform of Plasma Nocturnal Melatonin Secretion in Premenstrual Depression.
B. L. Parry, S. L. Berga, D. F. Kripke, M. R. Klauber, G. A. Laughlin, S. S. C. Yen, and J. C. Gillin (1990)
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Morning vs Evening Light Treatment for Winter Depression: Evidence That the Therapeutic Effects of Light Are Mediated by Circadian Phase Shifts.
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Corrections and Additions to the History of Light Therapy and Seasonal Affective Disorder.
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Bright light induction of strong (type 0) resetting of the human circadian pacemaker.
C. Czeisler, R. Kronauer, J. Allan, J. Duffy, M. Jewett, E. Brown, and J. Ronda (1989)
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Light Effects on Human Circadian Rhythms: A Review of Recent Andechs Experiments.
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Effects of Constant Darkness and Constant Light on Circadian Organization and Reproductive Responses in the Ram.
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