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Science 12 December 1980:
Vol. 210. no. 4475, pp. 1249 - 1251
DOI: 10.1126/science.6254153

Articles

Science, Vol 210, Issue 4475, 1249-1251
Copyright © 1980 by American Association for the Advancement of Science


articles

Transformation by cloned Harvey murine sarcoma virus DNA: efficiency increased by long terminal repeat DNA

EH Chang, RW Ellis, EM Scolnick, and DR Lowy

The coding sequences for the transforming (src) protein (p21) of Harvey murine sarcoma virus have been localized to a 1.3 kilobase pair segment near the 5' end of the viral genome. Ligation of the viral terminal repeat DNA to the left end of the src region DNA markedly enhanced the low transforming efficiency of the src region DNA.


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Transformation of human bronchial epithelial cells transfected by Harvey ras oncogene.
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