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Science 28 November 1980:
Vol. 210. no. 4473, pp. 1023 - 1025
DOI: 10.1126/science.7434012
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Articles

Science, Vol 210, Issue 4473, 1023-1025
Copyright © 1980 by American Association for the Advancement of Science

articles

Retinal tumor induced in the baboon by human adenovirus 12

N Mukai, SS Kalter, LB Cummins, VA Matthews, T Nishida, and T Nakajima

Three of 21 newborn baboons injected intraocularly with human adenovirus type 12 developed an intravitreal mass 12 to 36 months later. Two of the masses were indistinguishable from human retinoblastoma, a retinal tumor that afflicts children. To our knowledge this is the first time a retinoblastoma-like tumor has been induced experimentally by adenovirus type 12 in a nonhuman primate.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Retinoblastoma in a Dog.
N. A. Syed, T. M. Nork, G. L. Poulsen, R. C. Riis, C. George, and D. M. Albert (1997)
Arch Ophthalmol 115, 758-763
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