Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Site Tools

  • AAAS
  • Subscribe
  • Feedback

Site Search

Search Advanced

Science 21 November 1980:
Vol. 210. no. 4472, pp. 899 - 901
DOI: 10.1126/science.7434002
Prev | Table of Contents | Next

Articles

Science, Vol 210, Issue 4472, 899-901
Copyright © 1980 by American Association for the Advancement of Science

articles

Anesthetics as teratogens: nitrous oxide is fetotoxic, xenon is not

GA Lane, ML Nahrwold, AR Tait, M Taylor-Busch, PJ Cohen, and AR Beaudoin

Exposure of pregnant rats to the anesthetic nitrous oxide on the ninth day of gestation causes fetal resorption, skeletal anomalies, and macroscopic lesions including encephalocele, anophthalmia, microphthalmia, and gastroschisis. The inert gas xenon, which has anesthetic properties similar to those of nitrous oxide, does not cause teratogenic effects under the same experimental conditions.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
A Closed-Circuit Neonatal Xenon Delivery System: A Technical and Practical Neuroprotection Feasibility Study in Newborn Pigs.
E. Chakkarapani, M. Thoresen, C. E. Hobbs, K. Aquilina, X. Liu, and J. Dingley (2009)
Anesth. Analg. 109, 451-460
   Abstract »    Full Text »    PDF »
Remote Exposure to Xenon Produces Delayed Preconditioning Against Myocardial Infarction In Vivo: Additional Evidence That Noble Gases Are Not Biologically Inert.
P. S. Pagel (2008)
Anesth. Analg. 107, 1768-1771
   Full Text »    PDF »
The haemodynamic and catecholamine response to xenon/remifentanil anaesthesia in Beagle dogs.
R. C E Francis, M. S Reyle-Hahn, C. Hohne, A. Klein, I. Theruvath, B. Donaubauer, T. Busch, and W. Boemke (2008)
Lab Anim 42, 338-349
   Abstract »    Full Text »    PDF »
Xenon and Hypothermia Combine Additively, Offering Long-Term Functional and Histopathologic Neuroprotection After Neonatal Hypoxia/Ischemia.
C. Hobbs, M. Thoresen, A. Tucker, K. Aquilina, E. Chakkarapani, and J. Dingley (2008)
Stroke 39, 1307-1313
   Abstract »    Full Text »    PDF »
Xenon/Hypothermia Neuroprotection Regimes in Spontaneously Breathing Neonatal Rats After Hypoxic-Ischemic Insult: The Respiratory and Sedative Effects.
J. Dingley, C. Hobbs, J. Ferguson, J. Stone, and M. Thoresen (2008)
Anesth. Analg. 106, 916-923
   Abstract »    Full Text »    PDF »
The Effects of 30% and 60% Xenon Inhalation on Pial Vessel Diameter and Intracranial Pressure in Rabbits.
T. Fukuda, H. Nakayama, K. Yanagi, T. Mizutani, M. Miyabe, N. Ohshima, and H. Toyooka (2001)
Anesth. Analg. 92, 1245-1250
   Abstract »    Full Text »    PDF »
Xenon Has Greater Inhibitory Effects on Spinal Dorsal Horn Neurons than Nitrous Oxide in Spinal Cord Transected Cats.
Y. Miyazaki, T. Adachi, J. Utsumi, T. Shichino, and H. Segawa (1999)
Anesth. Analg. 88, 893
   Abstract »    Full Text »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)