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Science 7 November 1980:
Vol. 210. no. 4470, pp. 644 - 646
DOI: 10.1126/science.6107992
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Articles

Science, Vol 210, Issue 4470, 644-646
Copyright © 1980 by American Association for the Advancement of Science

articles

Somatostatin: occurrence in urinary bladder epithelium and renal tubules of the toad, Bufo marinus

JL Bolaffi, S Reichlin, DB Goodman, and JN Forrest Jr

Immunohistochemical techniques were used to detect immunoreactive somatostatin-like material in toad urinary bladder epithelium and in kidney distal tubules and collecting ducts. This material has immunological and chromatographic properties identical to those of synthetic cyclic somatostatin. The occurrence of somatostatin-like material in antidiuretic hormone-sensitive portions of the renal urinary system suggests a local regulatory or paracrine role for somatostatin.




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Science. ISSN 0036-8075 (print), 1095-9203 (online)