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Science 17 October 1980: Vol. 210. no. 4467, pp. 327 - 328 DOI: 10.1126/science.7423192
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Articles
Science, Vol 210, Issue 4467, 327-328
Copyright © 1980 by American Association for the Advancement of Science
Direct measurement of microvascular pressures in the isolated perfused dog lung
J Bhattacharya
and
NC Staub
Microvascular pressures in the pulmonary circulation were measured under the pleural surface of the isolated perfused dog lung by the servo-null technique. Strong glass micropipettes with short beveled tips were used, with a suction ring to stabilize the lung's surface. Of the total vascular resistance, 45 percent was in the alveolar wall capillaries themselves. Most of the remaining resistance was in the arterioles. There was negligible pressure drop in venules with diameters larger than 20 micrometers.
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