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Science 3 October 1980:
Vol. 210. no. 4465, pp. 74 - 76
DOI: 10.1126/science.6932101
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Articles

Science, Vol 210, Issue 4465, 74-76
Copyright © 1980 by American Association for the Advancement of Science

articles

Erythroid differentiation of clonal Rauscher erythroleukemia cells in response to erythropoietin or dimethyl sulfoxide

AJ Sytkowski, AJ Salvado, GM Smith, CJ McIntyre, and NJ deBoth

Clonal lines of Rauscher erythroleukemia cells exhibited selective responses to two inducers of differentiation, erythropoietin and dimethyl sulfoxide. There were substantial quantitiative differences between clones that reponded to both inducers. Several clones differentiated only in response to erythropoietin. Erythropoietin stimulated cell proliferation and differentiation whereas dimethyl sulfoxide inhibited proliferation, suggesting dissimilar modes of action.


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Novel Interaction between the Transcription Factor CHOP (GADD153) and the Ribosomal Protein FTE/S3a Modulates Erythropoiesis.
K. Cui, M. Coutts, J. Stahl, and A. J. Sytkowski (2000)
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Regulated Expression and Functional Role of the Transcription Factor CHOP (GADD153) in Erythroid Growth and Differentiation.
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Iron regulatory protein 1 is not required for the modulation of ferritin and transferrin receptor expression by iron in a murine pro-B lymphocyte cell line.
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Protein Kinase C-epsilon Is Necessary for Erythropoietin's Up-regulation of c-myc and for Factor-dependent DNA Synthesis. EVIDENCE FOR DISCRETE SIGNALS FOR GROWTH AND DIFFERENTIATION.
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