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Science 26 September 1980:
Vol. 209. no. 4464, pp. 1547 - 1548
DOI: 10.1126/science.7433978

Articles

Science, Vol 209, Issue 4464, 1547-1548
Copyright © 1980 by American Association for the Advancement of Science


articles

Anxiety and muscle tension as consequences of caffeine withdrawal

BC White, CA Lincoln, NW Pearce, R Reeb, and C Vaida

Regular consumers of caffeine had higher muscle tension after three or more hours of abstinence than low caffeine consumers. This difference was absent after double-blind administration of caffeine citrate or placebo. In a discriminative reaction time test, caffeine treatment improved performance. Among subjects receiving placebo, anxiety was highly correlated with prior caffeine use, suggesting that even a brief abstinence may produce anxiety in the regular user.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Caffeine withdrawal symptoms and rate of metabolism.
M. Lader, C. Cardwell, P. Shine, and N. Scott (1996)
J Psychopharmacol 10, 110-118
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Caffeine withdrawal: a contrast of withdrawal symptoms in normal subjects who have abstained from caffeine for 24 hours and for 7 days.
M. Bruce, N. Scott, P. Shine, and M. Lader (1991)
J Psychopharmacol 5, 129-134
   Abstract »    PDF »
Caffeine as an Analgesic Adjuvant.
E. M. Laska, A. Sunshine, F. Mueller, W. B. Elvers, C. Siegel, and A. Rubin (1984)
JAMA 251, 1711-1718
   Abstract »    PDF »
The Health Consequences of Caffeine.
P. W. CURATOLO and D. ROBERTSON (1983)
Ann Intern Med 98, 641-653
   Abstract »    PDF »



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Science. ISSN 0036-8075 (print), 1095-9203 (online)