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Science 19 September 1980:
Vol. 209. no. 4463, pp. 1401 - 1405
DOI: 10.1126/science.6106285
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Articles

Science, Vol 209, Issue 4463, 1401-1405
Copyright © 1980 by American Association for the Advancement of Science

articles

Chemical DNA synthesis and recombinant DNA studies

K Itakura and AD Riggs

Chemically synthesized DNA has been used in many recombinant DNA studies. These uses have included the total synthesis and cloning of functional genes, the cloning and expression of natural genes, and editing of changing genes by directed mutation.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Directed mutagenesis of dihydrofolate reductase.
J. Villafranca, E. Howell, D. Voet, M. Strobel, R. Ogden, J. Abelson, and J Kraut (1983)
Science 222, 782-788
   Abstract »    PDF »
Solid-phase Synthesis of Polynucleotides. VIII: A Simplified Synthesis of Oligodeoxyribonucleotides.
Z.-K. Tan, S. Ikuta, T. Huang, A. Dugaiczyk, and K. Itakura (1983)
Cold Spring Harb Symp Quant Biol 47, 383-391
   Abstract »    PDF »


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