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ArticlesCopyright © 1980 by American Association for the Advancement of Science
Cultivation in vitro of the quartan malaria parasite Plasmodium inui
The simian guartan malaria parasite Plasmodium inui (OS strain) was cultured in a continuous flow system with rhesus monkey erythrocytes and RPMI 1640nmedium supplemented with Hepes buffer and rhesus serum. Over a 10-week period, the growth of the parasite permitted a 61,000-fold cumulative dilution of the original inoculum. After 5 weeks in culture, the parasites were still infective to the monkey Saimiri sciureus and to Anopheles freeborni mosquitoes.
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Science. ISSN 0036-8075 (print), 1095-9203 (online)