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Science 12 September 1980:
Vol. 209. no. 4462, pp. 1240 - 1242
DOI: 10.1126/science.7403880
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Articles

Science, Vol 209, Issue 4462, 1240-1242
Copyright © 1980 by American Association for the Advancement of Science

articles

Human cutaneous lieshmania in a mouse macrophage line: propagation and isolation of intracellular parasites

KP Chang

A mouse macrophage line, J774G8, supports continuous and prolific intracellular growth of Leishmania mexicana amazonensis, the etiological agent of a South American cutaneous leishmaniasis. The intracellular parasites from these infected cultures can be isolated with high recovery rate and purity by simple Percoll gradient centrifugation.


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Pro-apoptotic effect of the landrace Bangla Mahoba of Piper betle on Leishmania donovani may be due to the high content of eugenol.
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Photodynamic Sensitization of Leishmania amazonensis in both Extracellular and Intracellular Stages with Aluminum Phthalocyanine Chloride for Photolysis In Vitro.
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Identification and Characterization of a Polyamine Permease from the Protozoan Parasite Leishmania major.
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Genetic characterization of glucose transporter function in Leishmania mexicana.
R. J. S. Burchmore, D. Rodriguez-Contreras, K. McBride, M. P. Barrett, G. Modi, D. Sacks, and S. M. Landfear (2003)
PNAS 100, 3901-3906
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N-Terminal Fatty Acid Substitution Increases the Leishmanicidal Activity of CA(1-7)M(2-9), a Cecropin-Melittin Hybrid Peptide.
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Episomal Expression of Specific Sense and Antisense mRNAs in Leishmania amazonensis: Modulation of gp63 Level in Promastigotes and Their Infection of Macrophages In Vitro.
D.-Q. Chen, B. K. Kolli, N. Yadava, H. G. Lu, A. Gilman-Sachs, D. A. Peterson, and K.-P. Chang (2000)
Infect. Immun. 68, 80-86
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Differential Regulation of Multiple Glucose Transporter Genes in Leishmania mexicana.
R. J. S. Burchmore and S. M. Landfear (1998)
J. Biol. Chem. 273, 29118-29126
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Genetic Analysis of Purine Metabolism in Leishmania donovani.
H.-Y. Hwang and B. Ullman (1997)
J. Biol. Chem. 272, 19488-19496
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A Family of Putative Receptor-Adenylate Cyclases from Leishmania donovani.
M. A. Sanchez, D. Zeoli, E. M. Klamo, M. P. Kavanaugh, and S. M. Landfear (1995)
J. Biol. Chem. 270, 17551-17558
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Intracellular Leishmania amazonensis amastigotes internalize and degrade MHC class II molecules of their host cells.
S De Souza Leao, T Lang, E Prina, R Hellio, and J. Antoine (1995)
J. Cell Sci. 108, 3219-3231
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Fusion between large phagocytic vesicles: targeting of yeast and other particulates to phagolysosomes that shelter the bacterium Coxiella burnetii or the protozoan Leishmania amazonensis in Chinese hamster ovary cells.
P. Veras, C de Chastellier, M. Moreau, V Villiers, M Thibon, D Mattei, and M Rabinovitch (1994)
J. Cell Sci. 107, 3065-3076
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Distribution of MHC class I and of MHC class II molecules in macrophages infected with Leishmania amazonensis.
T Lang, C de Chastellier, C Frehel, R Hellio, P Metezeau, S. Leao, and J. Antoine (1994)
J. Cell Sci. 107, 69-82
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Inhibition of leishmanias but not host macrophages by the antitubulin herbicide trifluralin.
M. Chan and D Fong (1990)
Science 249, 924-926
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Differential Expression of B1-containing Transcripts in Leishmania-exposed Macrophages.
Y. Ueda and G. Chaudhuri (2000)
J. Biol. Chem. 275, 19428-19432
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