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Science 12 September 1980:
Vol. 209. no. 4462, pp. 1197 - 1203
DOI: 10.1126/science.7403879
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Articles

Science, Vol 209, Issue 4462, 1197-1203
Copyright © 1980 by American Association for the Advancement of Science

articles

Estimating cancer risks from low doses of ionizing radiation

CE Land

Disagreements about the somatic risks from low doses of ionizing radiation stem from two difficulties fundamental to the logic of inference from observational data. First, precise direct estimation of small risks requires impracticably large samples. Second, precise estimates of low-dose risks based largely on high-dose data, for which the sample size requirements are more easily satisfied, must depend heavily on assumptions about the shape of the dose-response curve, even when only a few of the parameters of the theoretical form of the curve are unknown.


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