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Science 8 August 1980:
Vol. 209. no. 4457, pp. 715 - 717
DOI: 10.1126/science.7394533
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Articles

Science, Vol 209, Issue 4457, 715-717
Copyright © 1980 by American Association for the Advancement of Science

articles

Environmental influences on body weight and behavior in developing rats after neonatal 6-hydroxydopamine

DE Pearson, MH Teicher, BA Shaywitz, DJ Cohen, JG Young, and GM Anderson

There is less hyperactive motor activity and better avoidance performance in rat pups treated with 6-hydroxydopamine as neonates and reared with vehicle-treated littermates than in pups reared in litters composed solely of other 6-hydroxydopamine-treated animals. Thus, in this experimental model of hyperactivity, an environmental manipulation provides an alternative to pharmacologic agents in reducing activity and improving learning performance.




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Science. ISSN 0036-8075 (print), 1095-9203 (online)