Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Site Tools

  • AAAS
  • Subscribe
  • Feedback

Site Search

Search Advanced

Science 18 July 1980:
Vol. 209. no. 4454, pp. 418 - 420
DOI: 10.1126/science.7384816
Prev | Table of Contents | Next

Articles

Science, Vol 209, Issue 4454, 418-420
Copyright © 1980 by American Association for the Advancement of Science

articles

The testicular feminized rat: a naturally occurring model of androgen independent brain masculinization

BH Shapiro, DC Levine, and NT Adler

Although genotypically male (XY), the testicular feminized rat develops as an anatomic female because of an inherited deficiency in intracellular androgen receptors that prevents androgen imprinting of sexual primordia. However, the ability of testicular feminized rats to exhibit male-like sexual behavior and little feminine sexual behavior suggests that the brain can be masculinized without androgens.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Androgen-receptor defect abolishes sex differences in nitric oxide and reactivity to vasopressin in rat aorta.
J. N. Stallone, R. L. Salisbury, and C. T. Fulton (2001)
J Appl Physiol 91, 2602-2610
   Abstract »    Full Text »    PDF »
Gonadal hormones induce dendritic growth in the adult avian brain.
T DeVoogd and F Nottebohm (1981)
Science 214, 202-204
   Abstract »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)