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Science 6 June 1980:
Vol. 208. no. 4448, pp. 1161 - 1163
DOI: 10.1126/science.7189606
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Articles

Science, Vol 208, Issue 4448, 1161-1163
Copyright © 1980 by American Association for the Advancement of Science

articles

Vertical transmission of acquired ulcer susceptibility in the rat

NJ Skolnick, SH Ackerman, MA Hofer, and H Weiner

Premature separation of rat pups from their dams greatly increases their susceptibility to restraint-induced gastric erosions. When prematurely separated female rats grow to adulthood and mate with stock males, their normally reared F 1 progeny also have increased susceptibility to restraint-induced erosions. Cross-fostering studies show that prenatal rather than postnatal factors transmit this susceptibility to the F 1 progeny.




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Science. ISSN 0036-8075 (print), 1095-9203 (online)