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Science 7 March 1980:
Vol. 207. no. 4435, pp. 1083 - 1085
DOI: 10.1126/science.7355273
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Articles

Science, Vol 207, Issue 4435, 1083-1085
Copyright © 1980 by American Association for the Advancement of Science

articles

Local effect of the blastocyst on estrogen and progesterone receptors in the rat endometrium

F Logeat, P Sartor, MT Hai, and E Milgrom

Nuclear receptors for both estradiol and progesterone were present in twofold higher concentrations in implantation sites than in nonimplantation regions of the endometrium of 6-day pregnant rats. Decidualization in the absence of an embryo was not accompanied by a similar increase in the concentration of nuclear receptors. Moreover, this difference in receptor distribution between the implantation and nonimplantation areas persisted when a major part of the maternal supply of sex steroids was suppressed by ovariectomy on day 5 of pregnancy. These results support the hypothesis that steroids originating from the embryo affect the endometrial implantation site.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Estrogen receptors at implantation sites of rat endometrium.
F Logeat, P Sartor, M. Hai, and E Milgrom (1982)
Science 215, 1134-1135
   PDF »
Estrogen Receptors at Implantation Sites of Rat Endometrium.
D. MARTEL and A. PSYCHOYOS (1982)
Science 215, 1135
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Estrogen receptors in the nidatory sites of the rat endometrium.
D Martel and A Psychoyos (1981)
Science 211, 1454-1455
   Abstract »    PDF »


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