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Science 8 February 1980:
Vol. 207. no. 4431, pp. 649 - 651
DOI: 10.1126/science.6243417
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Articles

Science, Vol 207, Issue 4431, 649-651
Copyright © 1980 by American Association for the Advancement of Science

articles

Postsynaptic transmission block can cause terminal sprouting of a motor nerve

RL Holland and MC Brown

Sprouting of mouse soleus motor nerve terminals can be evoked by daily intramuscular injections of purified alpha-bungarotoxin. This finding supports the hypothesis that an important stimulus to terminal sprouting in partial denervation and presynaptic nerve blockade is a product of inactive muscle fibers.


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