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Science 30 November 1979:
Vol. 206. no. 4422, pp. 1091 - 1093
DOI: 10.1126/science.493995
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Articles

Science, Vol 206, Issue 4422, 1091-1093
Copyright © 1979 by American Association for the Advancement of Science

articles

Noncycling tumor cells are sensitive targets for the antiproliferative activity of human interferon

JS Horoszewicz, SS Leong, and WA Carter

Resting Burkitt's lymphoma cells (Daudi) in culture are more sensitive targets for the antiproliferative activity of purified human fibroblast interferon than cells that are rapidly multiplying. Thus, interferon may be of significant clinical value in neoplasms involving stem cells and, after chemotherapy, in suppressing the reemergence of tumors.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Human brain tumor--derived cell lines: growth rate reduced by human fibroblast interferon.
A. Cook, W. Carter, F Nidzgorski, and L Akhtar (1983)
Science 219, 881-883
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