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Science 30 November 1979:
Vol. 206. no. 4422, pp. 1083 - 1085
DOI: 10.1126/science.227060
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Articles

Science, Vol 206, Issue 4422, 1083-1085
Copyright © 1979 by American Association for the Advancement of Science

articles

Cerebral vessels have the capacity to transport sodium and potassium

HM Eisenberg and RL Suddith

The activity of Na+, K+-activated adenosinetriphosphatase and the uptake of a potassium analog, rubidium, were found to be similar in cerebral microvessels and choroid plexus when measured in vitro. This similarity suggests that sodium and potassium concentrations in the nascent brain extracellular fluid are determined by the same active process that regulates their concentration in nascent cerebrospinal fluid. The brain microvessels may thereby play on active role in brain potassium homeostasis and brain extracellular fluid formation.


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Transporters involved in regulation of intracellular pH in primary cultured rat brain endothelial cells.
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Ion Regulation in the Brain: Implications for Pathophysiology.
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