Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Site Tools

  • AAAS
  • Subscribe
  • Feedback

Site Search

Search Advanced

Science 16 November 1979:
Vol. 206. no. 4420, pp. 847 - 850
DOI: 10.1126/science.493986
Prev | Table of Contents | Next

Articles

Science, Vol 206, Issue 4420, 847-850
Copyright © 1979 by American Association for the Advancement of Science

articles

Activation of the supplementary motor area during voluntary movement in man suggests it works as a supramotor area

JM Orgogozo and B Larsen

Measurements of cerebral blood flow in man revealed that complex voluntary movements are associated with a blood flow increase in the supplementary motor area of the brain. This increase is additional to and similar in magnitude to the Rolandic sensorimotor area activation that occurs during all kinds of movement. When subjects counted silently there was no activation of any focal cortical area in the brain; when they counted aloud there was a marked increase in activity in the supplementary motor area. These results are consistent with the hypothesis that the supplementary motor area plays a major role in the initiation and control of at least some kinds of voluntary movement in man and is, therefore, a motor center of a higher order than the primary Rolandic areas.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Energy limitation as a selective pressure on the evolution of sensory systems.
J. E. Niven and S. B. Laughlin (2008)
J. Exp. Biol. 211, 1792-1804
   Abstract »    Full Text »    PDF »
Motor control in basal ganglia circuits using fMRI and brain atlas approaches.
S. Lehericy, E. Bardinet, L. Tremblay, P.-F. Van de Moortele, J.-B. Pochon, D. Dormont, D.-S. Kim, J. Yelnik, and K. Ugurbil (2006)
Cereb Cortex 16, 149-161
   Abstract »    Full Text »    PDF »
Supplementary Motor Area Activation in Patients with Frontal Lobe Tumors and Arteriovenous Malformations.
J. Sailor, M. E. Meyerand, C. H. Moritz, J. Fine, L. Nelson, B. Badie, and V. M. Haughton (2003)
AJNR Am. J. Neuroradiol. 24, 1837-1842
   Abstract »    Full Text »    PDF »
Activation of the Supplementary Motor Area (SMA) during Performance of Visually Guided Movements.
N. Picard and P. L. Strick (2003)
Cereb Cortex 13, 977-986
   Abstract »    Full Text »    PDF »
Neural Activity in Monkey Dorsal and Ventral Cingulate Motor Areas: Comparison with the Supplementary Motor Area.
G. S. Russo, D. A. Backus, S. Ye, and M. D. Crutcher (2002)
J Neurophysiol 88, 2612-2629
   Abstract »    Full Text »    PDF »
Role of the supplementary motor area in motor deficit following medial frontal lobe surgery.
A. Krainik, S. Lehericy, H. Duffau, M. Vlaicu, F. Poupon, L. Capelle, P. Cornu, S. Clemenceau, M. Sahel, C.-A. Valery, et al. (2001)
Neurology 57, 871-878
   Abstract »    Full Text »    PDF »
Movement-related change of electrocorticographic activity in human supplementary motor area proper.
S. Ohara, A. Ikeda, T. Kunieda, S. Yazawa, K. Baba, T. Nagamine, W. Taki, N. Hashimoto, T. Mihara, and H. Shibasaki (2000)
Brain 123, 1203-1215
   Abstract »    Full Text »    PDF »
A PET study of sequential finger movements of varying length in patients with Parkinson's disease.
M. J. Catalan, K. Ishii, M. Honda, A. Samii, and M. Hallett (1999)
Brain 122, 483-495
   Abstract »    Full Text »    PDF »
Role of the Supplementary Motor Area and the Right Premotor Cortex in the Coordination of Bimanual Finger Movements.
N. Sadato, Y. Yonekura, A. Waki, H. Yamada, and Y. Ishii (1997)
J. Neurosci. 17, 9667-9674
   Abstract »    Full Text »    PDF »
Motor Task Difficulty and Brain Activity: Investigation of Goal-Directed Reciprocal Aiming Using Positron Emission Tomography.
C. J. Winstein, S. T. Grafton, and P. S. Pohl (1997)
J Neurophysiol 77, 1581-1594
   Abstract »    Full Text »    PDF »
Treatment of Supplementary Motor Area Syndrome.
R. Hanlon, B. Clontz, D. Snow, and M. Thomas (1995)
Neurorehabil Neural Repair 9, 197-204
   Abstract »    PDF »
Supplementary and Primary Sensory Motor Area Activity in Parkinson's Disease: Regional Cerebral Blood Flow Changes During Finger Movements and Effects of Apomorphine.
O. Rascol, U. Sabatini, F. Chollet, P. Celsis, J.-L. Montastruc, J.-P. Marc-Vergnes, and A. Rascol (1992)
Arch Neurol 49, 144-148
   Abstract »    PDF »
Response Preparation and Response Inhibition After Lesions of the Medial Frontal Lobe.
M. Verfaellie and K. M. Heilman (1987)
Arch Neurol 44, 1265-1271
   Abstract »    PDF »
Apraxia and the Supplementary Motor Area.
R. T. Watson, W. S. Fleet, L. Gonzalez-Rothi, and K. M. Heilman (1986)
Arch Neurol 43, 787-792
   Abstract »    PDF »
Medial Frontal Cortex Infarction and the Alien Hand Sign.
G. Goldberg, N. H. Mayer, and J. U. Toglia (1981)
Arch Neurol 38, 683-686
   Abstract »    PDF »
Electrical potentials in human brain during cognition: new method reveals dynamic patterns of correlation.
A. Gevins, J. Doyle, B. Cutillo, R. Schaffer, R. Tannehill, J. Ghannam, V. Gilcrease, and C. Yeager (1981)
Science 213, 918-922
   Abstract »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)