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Science 16 November 1979:
Vol. 206. no. 4420, pp. 844 - 847
DOI: 10.1126/science.493985
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Articles

Science, Vol 206, Issue 4420, 844-847
Copyright © 1979 by American Association for the Advancement of Science

articles

Tumor location detected with radioactively labeled monoclonal antibody and external scintigraphy

B Ballou, G Levine, TR Hakala, and D Solter

Murine teratocarcinomas were located in mice by external gamma-ray scintigraphy with an iodine-125-labeled monoclonal antibody specific to the tumors. The specificity of the method was increased by subtracting the radiation produced by an iodine-125-labeled indifferent monoclonal antibody of the same immunoglobulin class as the tumor-specific antibody.


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S Ramakrishnan and L. Houston (1984)
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Activation and Regulation of Human Immune Responses: Implications in Normal and Disease States.
A. S. FAUCI, H. C. LANE, and D. J. VOLKMAN (1983)
Ann Intern Med 99, 61-75
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Monoclonal Antibodies.
B. Diamond and M. D. Scharff (1982)
JAMA 248, 3165-3169
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Use of Radiolabeled Antibodies for Localization of Neoplasms: The State of the Art.
P. Wolf and D. Reid (1981)
Arch Intern Med 141, 1067-1070
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Clinical radioimmunodetection of cancer with radioactive antibodies to human chorionic gonadotropin.
D. Goldenberg, E. Kim, F. DeLand, N. J. van Jr, and N Javadpour (1980)
Science 208, 1284-1286
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