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Science 2 November 1979:
Vol. 206. no. 4418, pp. 573 - 575
DOI: 10.1126/science.573922
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Articles

Science, Vol 206, Issue 4418, 573-575
Copyright © 1979 by American Association for the Advancement of Science

articles

Ethanol embryotoxicity: direct effects on mammalian embryos in vitro

NA Brown, EH Goulding, and S Fabro

Exposure to ethanol retards growth and differentiation in cultured rat embryos during organogenesis. The development of untreated embryos is indistinguishable from growth in utero. These data suggest that the hypoplastic features of children born to chronically alcoholic mothers are due, at least in part, to a direct action of ethanol, which causes reduced embryonic cellular proliferation early in gestation.


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Drug policy: striking the right balance.
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Effects of alcohol on the generation and migration of cerebral cortical neurons.
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Ethanol neurotoxicity: effects on neurite formation and neurotrophic factor production in vitro.
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Health Hazards Associated With Alcohol Consumption.
M. J. Eckardt, T. C. Harford, C. T. Kaelber, E. S. Parker, L. S. Rosenthal, R. S. Ryback, G. C. Salmoiraghi, E. Vanderveen, and K. R. Warren (1981)
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