Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Site Tools

  • AAAS
  • Subscribe
  • Feedback

Site Search

Search Advanced

Science 19 October 1979:
Vol. 206. no. 4416, pp. 292 - 297
DOI: 10.1126/science.113876
Prev | Table of Contents | Next

Articles

Science, Vol 206, Issue 4416, 292-297
Copyright © 1979 by American Association for the Advancement of Science

articles

Organization of the immune response genes

JW Uhr, JD Capra, ES Vitetta, and RG Cook

The I region of the major histocompatibility complex contains immune response genes that display considerable polymorphism; that is, there are many alleles at each locus. These genes regulate the immune response to antigen by mediating intercellular communication among lymphoreticular cells. An analysis of the primary structure of the products of two subregions of (I-A, I-E/C) was undertaken in order to understand the genetic organization of the region, the evolution of the genes and, eventually, their function.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Murine I-A beta chain polymorphism: nucleotide sequences of three allelic I-A beta genes.
E Choi, K McIntyre, R. Germain, and J. Seidman (1983)
Science 221, 283-286
   Abstract »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)