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Science 12 October 1979:
Vol. 206. no. 4415, pp. 230 - 232
DOI: 10.1126/science.482938
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Articles

Science, Vol 206, Issue 4415, 230-232
Copyright © 1979 by American Association for the Advancement of Science

articles

Exercise during development induces an increase in Purkinje cell dendritic tree size

JJ Pysh and GM Weiss

Mice allowed to exercise during the late postnatal period had Purkinje cells with larger dendritic trees and greater numbers of spines than littermates whose physical activity was severly restricted. These changes in Purkinje cells were accompanied by a selective reduction in the thickness of the cerebellar molecular layer. The data provide evidence for cerebellar plasticity during late development and demonstrate that physical activity can modify the development of Purkinje cell dendrites.


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