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Science 14 September 1979:
Vol. 205. no. 4411, pp. 1151 - 1153
DOI: 10.1126/science.382359
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Articles

Science, Vol 205, Issue 4411, 1151-1153
Copyright © 1979 by American Association for the Advancement of Science

articles

Pharmacologic effects in man of a potent, long-acting dopamine receptor agonist

L Lemberger and RE Crabtree

Single-dose administration of pergolide mesylate (100 to 400 micrograms) results in a dose-related inhibition of prolactin secretion which persists for more than 24 hours. During multiple-dose administration of pergolide, plasma prolactin concentrations remain markedly reduced (greater than 80 percnet) and gradually return to control levels several days after drug administration is discontinued.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Fluctuating Parkinson's Disease: Treatment With the Eong-Acting Dopamine Agonist Cabergoline.
J. E. Ahlskog, M. D. Muenter, D. M. Maraganore, J. Y. Matsumoto, A. Lieberman, K. F. Wright, and K. Wheeler (1994)
Arch Neurol 51, 1236-1241
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