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Science 14 September 1979:
Vol. 205. no. 4411, pp. 1138 - 1140
DOI: 10.1126/science.472733
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Articles

Science, Vol 205, Issue 4411, 1138-1140
Copyright © 1979 by American Association for the Advancement of Science

articles

Iodine-125--labeled estradiol: a gamma-emitting analog of estradiol that binds to the estrogen receptor

RB Hochberg

17 beta-[16 alpha-125I]Iodoestradiol has been synthesized by exchange of 16 beta-bromoestradiol with Na125I. The iodinated product is readily separated from the bromo reactant by column chromatography. It concentrates in the rat uterus in vivo and binds avidly and specifically to the uterine estrogen receptor in vitro.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Biologically Active Estrogen Receptor-{beta}: Evidence from in Vivo Autoradiographic Studies with Estrogen Receptor {alpha}-Knockout Mice.
P. J. Shughrue, M. V. Lane, and I. Merchenthaler (1999)
Endocrinology 140, 2613-2620
   Abstract »    Full Text »
Images of Estrogen-Receptor-Positive Breast Tumors Produced by Estradiol Labeled With Iodine I 123 at 16{alpha}.
D. E. Kenady, E. J. Pavlik, K. Nelson, J. R. van Nagell Jr, H. Gallion, P. D. DePriest, U. Y. Ryo, and R. J. Baranczuk (1993)
Arch Surg 128, 1373-1381
   Abstract »    PDF »


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