Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 24 August 1979:
Vol. 205. no. 4408, pp. 823 - 825
DOI: 10.1126/science.462193
Prev | Table of Contents | Next

Articles

Science, Vol 205, Issue 4408, 823-825
Copyright © 1979 by American Association for the Advancement of Science

articles

Menopausal flushes: a neuroendocrine link with pulsatile luteninizing hormone secreation

RF Casper, SS Yen, and MM Wilkes

Menopausal flush episodes were found to be invariably associated with the initiation of pulsatile pituitary release of luteinizing hormone. This was not accompanied by a significant change in circulating catecholamine or prolactin concentrations. Since pulsatile luteinizing hormone release results from episodic secretion of luteinizing hormone releasing factor by the hypothalamus, these findings suggest a link between the neuroendocrine mechanisms that initiate such episodic secretion and those responsible for the onset of flush episodes.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Luteinizing Hormone-Releasing Hormone and Postmenopausal Flushing.
H. de Boer, P. van Gastel, and A. van Sorge (2009)
N. Engl. J. Med. 361, 1218-1219
   Full Text »    PDF »
Menopausal Complaints Are Associated With Cardiovascular Risk Factors.
G.-C. M. Gast, D. E. Grobbee, V. J.M. Pop, J. J. Keyzer, C. J.M. Wijnands-van Gent, G. N. Samsioe, P. M. Nilsson, and Y. T. van der Schouw (2008)
Hypertension 51, 1492-1498
   Abstract »    Full Text »    PDF »
The Relationship of Longitudinal Change in Reproductive Hormones and Vasomotor Symptoms during the Menopausal Transition.
J. F. Randolph Jr, M. Sowers, I. Bondarenko, E. B. Gold, G. A. Greendale, J. T. Bromberger, S. E. Brockwell, and K. A. Matthews (2005)
J. Clin. Endocrinol. Metab. 90, 6106-6112
   Abstract »    Full Text »    PDF »
Lifestyle and Demographic Factors in Relation to Vasomotor Symptoms: Baseline Results from the Study of Women's Health Across the Nation.
E. B. Gold, G. Block, S. Crawford, L. Lachance, G. FitzGerald, H. Miracle, and S. Sherman (2004)
Am. J. Epidemiol. 159, 1189-1199
   Abstract »    Full Text »    PDF »
Estrogen Regulation of Neurokinin B Gene Expression in the Mouse Arcuate Nucleus Is Mediated by Estrogen Receptor {alpha}.
T. L. Dellovade and I. Merchenthaler (2004)
Endocrinology 145, 736-742
   Abstract »    Full Text »    PDF »
Pathophysiology and Treatment of Hot Flashes.
T. D. Shanafelt, D. L. Barton, A. A. Adjei, and C. L. Loprinzi (2002)
Mayo Clin. Proc. 77, 1207-1218
   Abstract »    PDF »
Distinguishing Features of Idiopathic Flushing and Carcinoid Syndrome.
L. B. Aldrich, A. R. Moattari, and A. I. Vinik (1988)
Arch Intern Med 148, 2614-2618
   Abstract »    PDF »
Estrogen Replacement Therapy: Indications and Complications.
H. L. JUDD, D. R. MELDRUM, L. J. DEFTOS, and B. E. HENDERSON (1983)
Ann Intern Med 98, 195-205
   Abstract »    PDF »
Flushing Reactions: Consequences and Mechanisms.
J. K. WILKIN (1981)
Ann Intern Med 95, 468-476
   Abstract »    PDF »
Association of Waking Episodes With Menopausal Hot Flushes.
Y. Erlik, I. V. Tataryn, D. R. Meldrum, P. Lomax, J. G. Bajorek, and H. L. Judd (1981)
JAMA 245, 1741-1744
   Abstract »    PDF »
Oral Medroxyprogesterone in the Treatment of Postmenopausal Symptoms.
I. Schiff, D. Tulchinsky, D. Cramer, and K. J. Ryan (1980)
JAMA 244, 1443-1445
   Abstract »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)