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Science 24 August 1979:
Vol. 205. no. 4408, pp. 823 - 825
DOI: 10.1126/science.462193
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Articles

Science, Vol 205, Issue 4408, 823-825
Copyright © 1979 by American Association for the Advancement of Science

articles

Menopausal flushes: a neuroendocrine link with pulsatile luteninizing hormone secreation

RF Casper, SS Yen, and MM Wilkes

Menopausal flush episodes were found to be invariably associated with the initiation of pulsatile pituitary release of luteinizing hormone. This was not accompanied by a significant change in circulating catecholamine or prolactin concentrations. Since pulsatile luteinizing hormone release results from episodic secretion of luteinizing hormone releasing factor by the hypothalamus, these findings suggest a link between the neuroendocrine mechanisms that initiate such episodic secretion and those responsible for the onset of flush episodes.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Menopausal Complaints Are Associated With Cardiovascular Risk Factors.
G.-C. M. Gast, D. E. Grobbee, V. J.M. Pop, J. J. Keyzer, C. J.M. Wijnands-van Gent, G. N. Samsioe, P. M. Nilsson, and Y. T. van der Schouw (2008)
Hypertension 51, 1492-1498
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The Relationship of Longitudinal Change in Reproductive Hormones and Vasomotor Symptoms during the Menopausal Transition.
J. F. Randolph Jr, M. Sowers, I. Bondarenko, E. B. Gold, G. A. Greendale, J. T. Bromberger, S. E. Brockwell, and K. A. Matthews (2005)
J. Clin. Endocrinol. Metab. 90, 6106-6112
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Lifestyle and Demographic Factors in Relation to Vasomotor Symptoms: Baseline Results from the Study of Women's Health Across the Nation.
E. B. Gold, G. Block, S. Crawford, L. Lachance, G. FitzGerald, H. Miracle, and S. Sherman (2004)
Am. J. Epidemiol. 159, 1189-1199
   Abstract »    Full Text »    PDF »
Estrogen Regulation of Neurokinin B Gene Expression in the Mouse Arcuate Nucleus Is Mediated by Estrogen Receptor {alpha}.
T. L. Dellovade and I. Merchenthaler (2004)
Endocrinology 145, 736-742
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Science. ISSN 0036-8075 (print), 1095-9203 (online)