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Science 10 August 1979:
Vol. 205. no. 4406, pp. 598 - 600
DOI: 10.1126/science.451624
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Articles

Science, Vol 205, Issue 4406, 598-600
Copyright © 1979 by American Association for the Advancement of Science

articles

Thyroid hormone influence on the susceptibility of mice to audiogenic seizures

TN Seyfried, GH Glaser, and RK Yu

Serum thyroxine levels peak earlier and are significantly higher in audiogenic seizure-susceptible DBA/2J mice than in seizure-resistant C57BL/6J mice during early postnatal life. The seizure susceptibility of DBA/2J mice is suppressed by administration of an antithyroid drug or by radiothyroidectomy, while the seizure susceptibility of C57BL/6J mice is enhanced by treatment with excess thyroxine.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Enhanced Susceptibility to Kainate-Induced Seizures, Neuronal Apoptosis, and Death in Mice Lacking Gangliotetraose Gangliosides: Protection with LIGA 20, a Membrane-Permeant Analog of GM1.
G. Wu, Z.-H. Lu, J. Wang, Y. Wang, X. Xie, M. F. Meyenhofer, and R. W. Ledeen (2005)
J. Neurosci. 25, 11014-11022
   Abstract »    Full Text »    PDF »
Type 2 iodothyronine deiodinase expression in the cochlea before the onset of hearing.
A. Campos-Barros, L. L. Amma, J. S. Faris, R. Shailam, M. W. Kelley, and D. Forrest (2000)
PNAS 97, 1287-1292
   Abstract »    Full Text »    PDF »


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